H. Lee Moffitt Cancer Center & Research Institute

Recent/relevant publication list:

1. Anderson AR, Hassanein M, Branch KM, Lu J, Lobdell NA, Maier J, Basanta D, Weidow B, Narasanna A, Arteaga CL, Reynolds AB, Quaranta V, Estrada L, Weaver AM. Microenvironmental independence associated with tumor progression. Cancer Res. 2009 Nov 15;69(22):8797-806.
2. Enderling H, Anderson AR, Chaplain MA, Beheshti A, Hlatky L, Hahnfeldt P. Paradoxical dependencies of tumor dormancy and progression on basic cell kinetics. Cancer Res. 2009 Nov 15;69(22):8814-21.
3. Basanta D, Strand DW, Lukner RB, Franco OE, Cliffel DE, Ayala GE, Hayward SW, Anderson AR. The role of transforming growth factor-beta-mediated tumor-stroma interactions in prostate cancer progression: an integrative approach. Cancer Res. 2009 Sep 1;69(17):7111-20.
4. Hinow P, Gerlee P, McCawley LJ, Quaranta V, Ciobanu M, Wang S, Graham JM, Ayati BP, Claridge J, Swanson KR, Loveless M, Anderson AR. A spatial model of tumor-host interaction: application of chemotherapy. Math Biosci Eng. 2009 Jul;6(3):521-46.
5. Ramis-Conde I, Chaplain MA, Anderson AR, Drasdo D. Multi-scale modelling of cancer cell intravasation: the role of cadherins in metastasis. Phys Biol. 2009 Mar 25;6(1):16008.
6. Gerlee P. & Anderson A. R. A. Evolution of cell motility in an individual-based model of tumour growth. J Theor Biol. 2009 Jul 7;259(1):67-83.
7. Anderson, A. R. A. & Quaranta, V. (2008) “Integrative Mathematical Oncology”, Nature Rev. Cancer, 8, 227-234

Arig Ibrahim Ashim, MD

1. Szebenyi G , Hall B , Yu R , Hashim AI , Kramer H . Hook2 Localizes to the Centrosome, Binds Directly to Centriolin/CEP110 and Contributes to Centrosomal Function. Traffic. 2007 Jan;8(1):32-46. Epub 2006 Nov 28.

2. Wang D, Stockard CR, Harkins L, Lott P, Salih C, Yuan K, Buchsbaum D, Ibrahim-Hashim A, Zayzafoon M, Hardy RW, Hameed O, Grizzle W, Siegal GP.  Immunohistochemistry in the Evaluation of Neovascularization in Tumor Xenografts: Antibody Selection and Antigen Retrieval Method Optimization. Biotechnic and Histochemistry 83:179-189, 2008

David Basanta

Recent/relevant publication list:

1. A game theoretical perspective on the somaticevolution of cancer. Chapter in In Selected topics on cancer modelling: genesis, evolution, inmune competition, therapy (N. Bellomo, M. Chaplain and E. De Angelis Eds.). Birkhauser, Boston.
2. Evolutionary game theory elucidates the role of glycolysis in glioma progression and invasion. D. Basanta, M. Simon, H. Hatzikirou and A. Deutsch. Cell Proliferation 41 (6) 980. 2008.
3. A game theoretical study of evolution of invasion in tumours. D. Basanta, H. Hatzikirou and A. Deutsch. Eur. Phys. Journal B 2008.
4. Robust homeostasis and wound healing in evolved artificial multicellular organisms. Basanta D, Miodownik M, Baum B (2008) The Evolution of Robust Development and Homeostasis in Artificial Organisms. PLoS Comput Biol 4(3): e1000030. doi:10.1371/journal.pcbi.1000030

Robert Gillies

Recent/relevant publication list:

1. Black K, Kirkpatrick N, Troutman T, Xu L, Vagner J, Gillies R, Barton J, Utzinger U, Romanowski M. Gold nanorods targeted to delta opioid receptor: plasmon-resonant contrast and photothermal agents. Mol Imaging. 2008 Jan;7(1):50-57. Pubmed ID: 18384724
2. Borden M, Zhang H, Gillies R, Dayton P, Ferrara K. A stimulus-responsive contrast agent for ultrasound molecular imaging. Biomaterials. 2008 Feb;29(5):597-606. Pubmed ID: 17977595
3. Fang J, Gillies R, Gatenby R. Adaptation to hypoxia and acidosis in carcinogenesis and tumor progression. Semin Cancer Biol. 2008 Mar 26; (3): . In Press. Pubmed ID: 18455429
4. Gatenby R, Gillies R. A microenvironmental model of carcinogenesis. Nat Rev Cancer. 2008 Jan;8(1):56-61. Pubmed ID: 18059462
5. Gillies R, Robey I, Gatenby R. Causes and consequences of increased glucose metabolism of cancers. J Nucl Med. 2008 Jun;49: 24S-42S. Pubmed ID: 18523064
6. Jennings D, Raghunand N, Gillies R. Imaging hemodynamics. Cancer Metastasis Rev. 2008 May 28; : . In Press. Pubmed ID: 18506397
7. Lope-Piedrafita S, Garcia-Martin M, Galons J, Gillies R, Trouard T. Longitudinal diffusion tensor imaging in a rat brain glioma model. NMR Biomed. 2008 May 12; (5): . In Press. Pubmed ID: 18470959
8. Moellering R, Black K, Krishnamurty C, Baggett B, Stafford P, Rain M, Gatenby R, Gillies R. Acid treatment of melanoma cells selects for invasive phenotypes. Clin Exp Metastasis. 2008;25(4):411-425. Pubmed ID: 18301995
9. Vagner J, Xu L, Handl H, Josan J, Morse D, Mash E, Gillies R, Hruby V. Heterobivalent ligands crosslink multiple cell-surface receptors: the humanme lanocortin-4 and delta-opioid receptors. Angew Chem Int Ed Engl. 2008;47(9):1685-1688. Pubmed ID: 18205159

Bob Gatenby

Recent/relevant publication list:

1. Fang J, Gillies RJ, Gatenby RA Adaptation to hypoxia and acidosis in carcinogenesis and tumor progression. Seminars in Cancer Biology, 2008.
2. Gillies RJ, Robey I, Gatenby RA Causes and consequences of increased glucose metabolism of cancers. Journal of Nuclear Medicine 49(2):24S-42S, 2008.
3. Gatenby RA, Gillies RJ. A microenvironmental model of carcinogenesis. Nat Rev Cancer. 8(1):56-61, Jan 2008.
4. Huang L, Lai Y-C, Gatenby RA Alternating synchronizability of complex clustered networks with regular local structure. Phys Rev E Stat Nonlin Soft Matter Phys. 77:016103, 2008.
5. Moellering RE, Black KC, Krishnamurty C, Baggett BK, Stafford P, Rain M, Gatenby RA, Gillies RJ. Acid treatment of melanoma cells selects for invasive phenotypes. Clin Exp Metastasis. 25(4):411-25, 2008.
6. Vincent TL, Gatenby RA An evolutionary model for initiation, promotion, and progression in carcinogenesis. International Journal of Oncology. 32:729-737, 2008.
7. Frieden BR, Gatenby RA. Equations of Biological Population Growth from Hartree Scattering. Accepted Physical Review E.
8. Vincent, TL, Gatenby, RA, Somatic evolution of cancer. International Game Theory Review. 10(1): 101-118, 2008.
9. Gatenby RA, Frieden BR. Inducing catastrophe in malignant growth. Mathematical Medicine & Biology. 2008.
10. Smallbone K, Gatenby RA, Maini PK. Mathematical modeling of tumor acidity. Accepted to Journal of Theoretical Biology. 2008.
11. Robey IF, Stephen RM, Brown KS, Baggett BK, Gatenby RA, Gillies RJ. Regulation of the Warburg effect in early-passage breast cancer cells. Neoplasia. 10(8):745-56, 2008.
12. Fang JS, Gillies RD, Gatenby RA. Adaptation to hypoxia and acidosis in carcinogenesis and tumor progression. Seminars in Cancer Biology. 18:330-337, 2008.
13. Gillies RJ, Robey I, Gatenby RA. Causes and consequences of increased glucose metabolism of cancer. J Nucl Med. 2:24S-42S, 2008.

Yoonseok Kam

Recent/relevant publication list:

1. Kam Y, Guess C, Estrada L, Weidow B, Quaranta V. A novel circular invasion assay mimics in vivo invasive behavior of cancer cell lines and distinguishes single-cell motility in vitro. BMC Cancer. 2008 Jul 14;8:198.
2. Jourquin J, Yang N, Kam Y, Guess C, Quaranta V. Dispersal of epithelial cancer cell colonies by lysophosphatidic acid (LPA). J Cell Physiol. 2006 Feb;206(2):337-46.
3. Kam Y, Exton JH. Role of phospholipase D1 in the regulation of mTOR activity by lysophosphatidic acid. FASEB J. 2004 Feb;18(2):311-9.

Virendra Kumar

Recent/relevant publication list:

1. Jagannathan NR, Kumar V, Kumar R, Thulkar S. Role of magnetic resonance (MR) methods in the evaluation of prostate cancer: An Indian perspective. MAGMA 2008 Epub PMID:18633658.
2. Kumar V, Jagannathan NR, Kumar R, Thulkar S, Gupta SD, Hemal AK, Gupta NP. Evaluation of the role of magnetization transfer imaging in prostate: A preliminary study. Magnetic Resonance Imaging 2008; 26(5): 644-649.
3. Kumar V, Jagannathan NR, Kumar R, Thulkar S, Gupta SD, Hemal AK, Gupta NP. Transrectal ultrasound-guided biopsy of prostate voxels identified as suspicious of malignancy on three-dimensional 1H MR spectroscopic imaging in patients with abnormal digital rectal examination or raised prostate specific antigen level of 4 -10 ng/ml. NMR in Biomedicine 2007; 20:11-20.
4. Kumar V, Jagannathan NR, Kumar R, Thulkar S, Gupta SD, Dwivedi SN, Hemal AK, Gupta NP. Apparent diffusion coefficient of prostate in men prior to biopsy: Determination of a cut-off value to predict malignancy of the peripheral zone. NMR in Biomedicine 2007; 20: 505-511.
5. Kumar R, Nayyar R, Kumar V, Gupta NP, Hemal AK, Jagannathan NR, Gupta SD, Thulkar S. The potential of magnetic resonance spectroscopic imaging in predicting absence of prostate cancer in men with serum prostate specific antigen between 4-10 ng/mL: a follow up study. Urology 2008 Epub PMID 18329078.
6. Sinha S, Kumar V, Jagannathan NR, Pandey RM. Proton magnetic resonance spectroscopy of brain to study the cerebral abnormalities in COPD patients: A case control study in North India. Indian Journal of Chest Diseases and Allied Sciences 2008 (In Press).
7. Sinha S, Misra A, Rathi M, Kumar V, Pandey RM, Luthra K, Jagannathan NR. Proton magnetic resonance spectroscopy and biochemical investigation of type 2 diabetes mellitus in Asian Indians: observation of high muscle lipids and C-reactive protein levels. Magnetic resonance Imaging 2008 Epub PMID 18687549.

Dave Morse

Recent/relevant publication list:

1. Morse DL, Galons J-P, Payne C, Jennings D, Day Sam, Xia G, Gillies RJ. MRI-measured water mobility increases in response to chemotherapy via multiple cell-death mechanisms. NMR Biomed. 2007; 20: 602-614.
2. Morse DL, Raghunand N, Sadarangani P, Murthi S, Job C, Day S, Howison C, Gillies RJ. Response of choline metabolites to docetaxel therapy is quantified in vivo by localized 31P MRS of human breast cancer xenografts and in vitro by high-resolution 31P NMR spectroscopy of cell extracts. Magn Reson Med. 2007; 58(2): 270-80.
3. Vagner J, Xu L, Handl HL, Josan JS, Morse DL, Mash EA, Gillies RJ, Hruby VJ. Heterobivalent Ligands Crosslink Multiple Cell-Surface Receptors: The Human Melanocortin-4 and delta-Opioid Receptors. Angew Chem Int Ed Engl. 2008; 47(9): 1685-8.
4. Han H, Gillies RJ, Morse DL, Hruby VJ. Patent: Method of Identifying Pancreatic Cancer Cells. 2008.
5. Balagurunathan Y, Morse DL, Hostetter G, Shanmugam V, Stafford P, Shack S, Pearson J, Trissal M, Demeure MJ, Von Hoff DD, Hruby VJ, Gillies RJ, Han H. Gene expression profiling-based identification of cell-surface targets for developing multimeric ligands in pancreatic cancer. Mol Cancer Ther. 2008; 7(9): 3071-80.
6. Morse DL, Carroll D, Day S, Gray H, Sadarangani P, Murthi S, Job C, Baggett B, Raghunand N, Gillies RJ. Characterization of breast cancers and therapy response by MRS and quantitative gene expression profiling in the choline pathway. NMR Biomed. 2008 (in press).

Katarzyna A. Rejniak

Recent/relevant publication list:

1. Rejniak K.A., S.E. Wang, N.S. Bryce, H. Chang, B. Parvin, J. Jourquin, L. Estrada, J.W. Gray, C.L. Arteaga, A.M. Weaver, V. Quaranta, A.R.A. Anderson, Linking Changes in Epithelial Morphogenesis to Cancer Mutations Using Computational Modeling, PLoS Computational Biology, 2010, 6(8):e1000900
2. Rejniak K.A., A.R.A. Anderson, Multiscale hybrid models of tumor growth, Wiley Interdisciplinary Reviews: System Biology and Medicine, in press
3. Rejniak K.A., McCawley L.J., Current trends in mathematical modeling of tumor-microenvironment interactions: a survey of tool and applications, Experimental biology and Medicine, 235:411-423, 2010 
4. Anderson, A.R.A., Rejniak, K.A., Gerlee, P., Quaranta, V., Microenvironment driven invasion: a multiscale multimodel investigation, Journal of Mathematical Biology, 58:579-624, 2009
5. Quaranta, V., Rejniak, K.A., Gerlee, P., Anderson, A.R.A, Invasion emerges from cancer cell adaptation to competitive microenvironments: Quantitative predictions from multiscale mathematical models., Seminars in Cancer Biology, 18:338-348, 2008
6. Rejniak, K.A., Anderson, A.R.A, A computational study of the development of epithelial acini. I. Sufficient conditions for the formation of a hollow structure, Bulletin of Mathematical Biology, 70(3):677–712, 2008
7. Rejniak, K.A., Anderson, A.R.A., A computational study of the development of epithelial acini. II. Necessary conditions for structure and lumen stability, Bulletin of Mathematical Biology, 70(5):1450–1479, 2008
8. Anderson, A.R.A, Rejniak, K.A., Gerlee, P., Quaranta, V., Modelling of cancer growth, evolution and invasion: bridging scales and models, Mathematical Modelling of Natural Phenomena, 2(3):1-29, 2007

Amanda Shanks

  Liping Xu